With the rapid expansion of the human civilization there has also been a vast growth of new forms of diseases that are posing a grave impending danger before the posterity. One of the most pertinent of all diseases is regarding the blood vessels and its various dimensions, most of which regarding the adult stem cells. Now according to a new research it has come to the fore, that the very blood vessels that have been tissue-engineered from bone marrow adult stem cells may have the potential to operate as the respective blood vessels of the patient in the long run, but is only possible if there happens a coronary bypass or any other form of surgical intervention in order to reinstate the vessel. It is to be cited, that the central initiative has been taken by the eminent scientists hailing from the University at Buffalo ( N.Y.) Department of Chemical and Biological Engineering and they have developed a specific methodology for the fabrication of blood vessels tissue-engineered from bone marrow adult stem cells.

In a brief manner the investigative research explains the anticipation for the growth of tissue-engineered vessels out of stem cells that are garnered from the patients who are in great need of them. This very course of action however provides an advantageous option to the venous grafts, which is at present done more often than not in patients going through coronary bypass operations. The shortcomings that are inseparable related with venous grafts consist of limited availability of vessels, pain and discomfort at the donor site and a high 10-year failure rate. In addition the group of researchers from the University at Buffalo developed an innovative method meant for the isolation of functional smooth muscle cells from the bone marrow. The entire scheme was developed through the effective utilization of a fluorescent marker protein and a tissue-specific promoter for alpha-actin, a protein found in muscles that is responsible for their ability to contract and relax.

Speaking on the occasion, Dr. Stelios T. Andreadis, the eminent Associate Professor and also on of the prominent figures in the investigative group said, "Our results show that bone marrow is an excellent source of adult stem cells containing smooth muscle and endothelial cells, and that these stem cells can be used in regenerative medicine for cardiovascular applications."