In the past the notion of upsetting a stem cell from its preliminary dormant state was once thought to contaminate its gold-standard properties. But in the recent days that age old conception has drastically changed thanks to the research that has exhibited in the recent days the manner in which a signaling pathway happens to regulate the stem cell behavior. It has also revealed prolifically that the stem cells getting activate even for once have the sufficient potential to enter the perfect gamut of time within which they respond to their environment and at the same time retain their ability for the basic alteration of their developmental path.

It is to noted that the investigative study has been done by an eminent group of scientists at the Rockefeller University under the leadership of Elaine Fuchs. Through a discourse with the leading members of the team it is learnt that that ye have found that Bone Morphogenetic Protein or the BMP conduit needs to be turned on and off at the right time and at the right place for adult skin stem cells for the sake of becoming hair follicles.

Speaking on the occasion the most prominent author of the research team Dr. Kris Kobielak, a former postdoc in Fuchs' lab said,   "These stem cells preferentially become hair follicles, but are capable of redirecting their developmental course and becoming skin cells when needed; if epidermal skin stem cells are not around to repair a wound on the surface of the skin, these hair follicle stem cells become reprogrammed to make epidermis."

To the researchers from its discovery and commencement in the year 1965 the BMP pathway has been found to standardize the cell proliferation and differentiation in many tissues that also includes the hair follicle. However, thus far the researchers were not even aware about its mode of controlling the stem cell behavior during the hair cycle. Whereas in the adult skin each hair follicle tend to contain a reservoir of stem cells called the bulge. With the receiving of the proper signals by the bulge there begins a form of proliferation on the part of the stem cells into progenitor cells followed by the differentiation of the hair follicles.