It has been found that the eminent group of biologists of Pennsylvania have come out with a new study report that that the sheer explanation to the liver's phenomenal aptitude towards the novel process of repairing itself could be cells migrating from the bone marrow. It is to be noted, that the liver being one of the most vital organs n any human body is called the "comeback kid" and is said to have the potential of amazing feats of regeneration.

According to the specific group of eminent biologists, there have been ample instances hat have demonstrate for time and again that if two-thirds of a rat's liver gets removed, the organ will grow up back to normal size and that takes place or occurs within the stipulated time of only one week. It has been stressed that this implausible rejuvenation happens mainly due to the bizarre knack of the specialized liver cells, better known as hepatocytes, in order to sustain the mode of dividing. But the organ repairs itself even in animals given drugs to prevent this occurring, which shows that other cell types must be involved.

While going through the past records in order to ascertain the initiation of this very research it is found that the first evidences regarding identity of these liver stem cells came to the fore in the 1950s. at that period it originated from the studies of tumors that tend to mature from another type of cell found in the liver that are generally called the oval cells. It is found that these cancers are comprised of some cells that give the impression of being mature hepatocytes and others while resembling to the cells that line the bile duct depositing the liver's waste products into the intestine. This is an ample proof that the elusive liver stem cells at the outset tend to give rise to the oval cells, which in due course give rise to the division and differentiation towards the formation of hepatocytes and bile duct cells.

On the very last year, the eminent researcher Bryon Petersen of the University of Pittsburgh in conjunction with his colleagues accomplished the discovery that oval cells have a "marker" molecule on their surfaces which also available on haematopoietic stem cells, the cells present in the bone marrow of the human beings helping the rise to blood cells.