It has been confirmed by a group of scientists through the utilization of a definite process of genetic analysis, that a human embryonic stem cell line supposedly developed by the acclaimed scientists of Korea though the usage of cloning techniques was actually derived from unfertilized eggs. In this regard the scientists have confirmed in the recent days that the Human ES cells are on average made from embryos that are usually donated by those couples who have gone through the methodology of vitro fertilization. On the other hand, the Parthenogenetic ES (pES) cells are derived from that are usually created by the process of the artificial creation of eggs in the absence of sperm.

What are ES cells then? The ES cells in general are engendered by the somatic nuclear transfer or ntES. They are derived from embryos that are created at opportune moment when the nucleus of an egg gets replaced by the nucleus from a body cell. It is to be noted in this sphere that the fabrication of ntES and pES cells are of particular interest to researchers for their availability in providing the stem cells that are almost genetically matching to the donor and are also compatible for an assortment of processes like the customized, rejection-proof cell transplantation therapies.

Even so, for a better comprehension of the definite inherent recombination events occurring in ES cells and also derived by these diverse methods, under the guidance of Dr. George Q. Daley of Children's Hospital Boston and the Harvard Stem Cell Institute the researchers in concert with other renowned associates went through the completion of a methodical genome-wide analysis. They were consisted of five new pES cells, 30 mouse ntES, in addition to the SCNT-hES-1 cell line, the first human ES cell line allegedly generated by Korean scientists through the using of human eggs and somatic cell nuclear transfer.

Speaking on the occasion Dr. Daley said, "Our analysis shows that the recombination pattern of SCNT-hES-1 is distinct from that of an ntES line and is consistent with its derivation from a parthenogenetic embryo. Thus, we conclude that the derivation of SCNT-hES-1 represented the first successful isolation of human pES cells." "If careful genetic and functional analysis of tissues derived from human pES cells show them to be safe and effective, then pES cells might represent a favorable source for tissue replacement therapies," he concluded.