Though in this age of Web based technology each and every info is readily available at the click of the mouse, however there is a growing need of the preservation of the valuable specimens of the spectacular advancements in the realm of medical science. It is in this regard that the National Library of Medicine, the noteworthy constituent institute of the National Institutes of Health or the NIH has come out with the announcement of the publication of selected works from the papers of Sol Spiegelman. It is to be noted in this regard, that Sol Spiegelman was a pioneer in the discipline of molecular biology and it were his discoveries that assisted immensely in the revelation of the mechanisms of gene action leading to the foundation of the recombinant DNA technology. On the other hand, with this very addition the prestigious collection of the well-known researchers, public health officials, and promoters of medical research has been elevated to a substantial level. 

To inform the readers of Sol Spiegelman it must be cleared at the outset of a young age it was his summer work hospital research labs that sparked Spiegelman 's profound interest in bacterial mutations. His Post Doctoral research beginning at the Columbia University, and getting completed in 1944 at Washington University in St. Louis and went through a meticulous way of verification that even it was possible for the bacteria to adapt itself for sometimes with the general presence novel nutrient substances through the production of the enzymes necessary for the sake of digesting them but without moving through the process of a genetic mutation. In the later period of his life he became instrumental in the exhibition of genes for making various enzymes that could be turned off and on by the sheer occurrence of different nutrients. This very methodology, called enzyme induction through the gradual years was converted into a potent device for the methodical comprehension of the encoding of the DNA and its way of being transcribed to produce enzymes so as to contribute in the direct cellular life processes.

Speaking on the occasion Dr. Donald A. B. Lindberg, M.D., and Director of the National Library of Medicine said, "Sol Spiegelman was an extraordinarily creative scientist; his achievements include the first test-tube synthesis of an infective virus RNA and the development of RNA-DNA hybridization, an essential technique in molecular biology."