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Mouse Strain DNA Will Help to Identify Environmental Disease |
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Written by Subhasis Chatterjee
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It is greatly anticipated by the scientists that their researched conducted on the DNA of 15 mouse strains that are generally used in biomedical studies will help them a lot for the specific determination of genes that are related to the vulnerability to the various types of environmental diseases. The entire testimony of data, to the researchers, is available to the public view in a catalog of genetic variants that in due course exhibits the statistics in the form of a mouse haplotype map, a specific device tat do differentiate chromosomes in to many small segments assisting in a great extent for the proper identification of genes genetic variations in mice that may perhaps affect health and disease. In addition, this haplotype map will be available in the coming days in an online version full descriptive analysis of the "Mouse Genome Resequencing and SNP Discovery Project." In this sphere it is worth mentioning that the study has been conducted by the National Institute of Environmental Health Sciences (NIEHS), one of the renowned components of the National Institutes of Health.
It has been learnt that the study meticulously explains the arduous and technology-driven approaches whose effective utilization has been perceived in the identification of 8.27 million high quality SNPs distributed among the genomes of 15 mouse strains. But to enquire about the SNPs it is better to know that they happen to be better known as the Single Nucleotide Polymorphisms (known as snips), which are single genetic changes, or variations and that have the capability to come about in a DNA sequence. What's more, a great part of the project was conducted through a contract between the National Toxicology Program at NIEHS and Perlegen Sciences, Inc. of Mountain View Calif.
Speaking on the occasion, Dr. David A. Schwartz., MD and Director of the NIEHS said, "These data allow researchers to compare the genetic makeup of one mouse strain to another, and perform the necessary genetic analyses to determine why some individuals might be more susceptible to disease than another. This puts us one step closer to understanding individual susceptibility to environmental toxins in humans. We also hope that pharmaceutical companies developing new treatments for environmental diseases will find these data and this paper as a valuable resource."
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