• Narrow screen resolution
  • Wide screen resolution
  • Auto width resolution
  • Increase font size
  • Decrease font size
  • Default font size
  • default color
  • red color
  • green color
Member Area

Cord Blood Report

Tuesday
Nov 18th
Home
Innovative Dimension In Gene Research PDF Print E-mail
Written by Subhasis Chatterjee   

After a long wait there is a new finding which has been able to pose a serious challenge to a firm conviction of long days. Till now there has been a general supposition that there many genes in human body that in real terms hang around between the aspects of "on" and "off" in any specified cell resulting into the readiness for further action. However, the new finding has been able to contradict this conjecture held for long that the sheer process of turning over a cell's "on-off" switch happens to control the production of a particular regulatory protein of a cell. The new study was undertaken by an eminent group of scientists in the lab of Richard Young at the Whitehead Institute for Biomedical Research in Cambridge, Mass, where they came to the conclusion that these very genes do initiate the making of RNA templates for proteins, a distinct methodology that was termed transcription, though it was found to fail while finishing.

While going through the discourse with the scientists it has come to the revelation that in a general human body here happens to be the existence of huge numbers of cells that number not less than at least 200. At the same note, it is striking that each cell is comprised of the identical complete set of genes, but in due course happens to express only a exclusive fraction of them, which in its turn manufacture proteins that formulate in the formation of nerve or skin or white blood cell. For years it has been known by the scientists that a cell hide from view the genes it doesn't need by coiling the dormant DNA tightly around protein spools called histones.

In this very approach, the innovative analysis, on the other hand, puts forward that DNA packaging remains loose at the commencement of many inactive genes, differing in complete sense from the prescribed models in the textbooks of the educational curriculum. The postdoctoral researchers Matthew Guenther and Stuart Levine of the Whitehead Institute displayed the entire human genome for a chemical signature or "landmark" that do remain in acquaintance with this looser DNA packaging configuration and thus with transcription initiation. The duo, according to their own versions, worked with embryonic stem cells, liver cells and white blood cells.

Speaking on this novel introduction of a new study that has been able to pose a challenge to the long preserve opinion Dr. Richard Young, who also happens to be a well known MIT professor of biology said, "Surprisingly, about one-third of our genes, including all the regulators of cell identity, fall into this new class." "It seems awfully risky for an adult cell to leave genes primed that could change its identity," he concluded.

 

 
< Prev   Next >
Advertisement
 

Email Updates

Enter your email address:

Main Menu

Home

Login Form






Lost Password?
No account yet? Register

Syndicate

Search